If you own the physical cartridge, dumping your own NSP and applying the update via a clean dump is the safest method. However, for those seeking the "Scene" release, look for the group or "SUXXORS" —their recent repack includes the base NSP + UPD pre-patched into a single file, removing the need to install two separate items.

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Downloading a "base" NSP often means you are missing critical patches. For this collection, an "Updated NSP" (often labeled as v1.0.1 or higher, or bundled with the DLCs in a "Multi-Pack" NSP) is essential for the best experience because:

Here's some good content about Assassin's Creed: The Ezio Collection on the Nintendo Switch: