If your goal is to avoid the launcher's online requirements or frequent crashes related to the DRM, you can force the game into offline mode:
There is no official or legal way to play Splinter Cell: Blacklist splinter cell blacklist without uplay
However, Uplay (Ubisoft Connect) is a resource hog that provides zero value to the single-player experience. If your goal is to avoid the launcher's
If you are looking for ways to play without the launcher due to crashes or connection errors, the following community-suggested methods may help: Offline Shortcut Method splinter cell blacklist without uplay