The PC version of Substance was originally released in 2003. It was notorious for being a "buggy port" with major issues on modern hardware.
: Run the new MGS2SSetup.exe to select your resolution and controller layout (the "Original PS2 Layout" is highly recommended for authenticity). file metalgearsolid2substancev10zip 2021
Modified files that allow the game to run without the original physical disc, which is necessary for modern laptops that lack disc drives. Modern Alternatives The PC version of Substance was originally released in 2003
