If you still have the USB eLicenser dongle and an older macOS (Mojave or earlier), possibly. But no official support exists for modern Macs.
Downloading and Installing reFX Nexus 2 on macOS While it remains a staple for many electronic music producers, the official method for downloading and installing it has transitioned to modern cloud-based tools. Official Download Link & Access download vst nexus 2 mac link
