Pharmacology In Drug Discovery And Development //free\\

This is the study of the biochemical and physiological effects of a drug. In the discovery phase, pharmacologists identify a "target"—usually a protein, receptor, or enzyme involved in a disease process. They ask: Does this molecule bind to the target? Does it turn the target on (agonist) or turn it off (antagonist)? Pharmacodynamics defines the therapeutic window, determining the range of dosage that provides efficacy without toxicity.